The pancreas is an organ in the body that secretes several hormones, including insulin and glucagon, as well as digestive enzymes that help break down food. Insulin helps cells in the body take up glucose (sugar) from the blood to use for energy, which lowers blood glucose levels. Glucagon causes the liver to release stored glucose, which raises blood glucose levels.
Type 1 diabetes occurs when the pancreas produces little or none of the insulin needed to regulate blood glucose. Type 2 diabetes occurs when the pancreas does not produce enough insulin or the body becomes resistant to the insulin that is present. Patients with type 1 diabetes and some patients with type 2 diabetes inject insulin, and occasionally glucagon, to regulate their blood glucose, which is critical to lower their risk of long-term complications such as blindness, kidney failure and cardiovascular disease.
When managing diabetes, many patients must vigilantly test blood glucose with a glucose meter, calculate insulin doses, and administer necessary insulin doses with a needle or insulin infusion pump to lower blood glucose. Glucagon may be injected in an emergency to treat severe low blood glucose. Some patients benefit from additional monitoring with a continuous glucose monitoring system.
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